Brian K. Firestone, MD

Clinical Associate Professor

Clinical Focus

Special Interests

  • Intraocular tumors, including uveal nevus, melanoma, retinoblastoma, metastatic tumors, lymphoma, retinal vascular tumors, rare tumors, and simulating lesions (e.g. Coats disease, FEVR).
  • Ocular surface tumors, including conjunctival melanoma, squamous neoplasia, lymphoma, and others.
  • Specific training in fine-needle aspiration biopsy of intraocular tumors, plaque radiotherapy, transpupillary thermotherapy, laser photocoagulation, photodynamic therapy, cryotherapy, and intravitreal chemotherapy injection.
  • Ophthalmic pathology, including gross and microscopic evaluation and special stains.
  • Cataract and intraocular lens implant surgery, including radiation-related cataract.


  • BA: Oklahoma Baptist University (magna cum Laude, with honors), Shawnee, OK – 2004
  • MD: University of Oklahoma College of Medicine, Oklahoma City, OK – 2008
  • Preliminary Internal Medicine: Scott & White Memorial Hospital, Temple, TX – 2008-2009
  • Ophthalmology Residency: Scott & White Memorial Hospital, Temple, TX – 2009-2012
  • Ocular Oncology Fellowship: Wills Eye Hospital, Philadelphia, PA – 2012-2013
  • Ocular Pathology Fellowship: Wills Eye Hospital, Philadelphia, PA – 2013


Dr. Firestone is a native of southern Oklahoma and received his undergraduate education at Oklahoma Baptist University, where he received the William Neptune Distinguished Alumni Award in 2014. He received his medical training at the University of Oklahoma. He served as chief resident during his ophthalmology residency at the Scott and White Eye Institute at Texas A&M University. He served as clinical fellow on the Oncology Service at Wills Eye Hospital under the direction of Jerry A. Shields, MD and Carol L. Shields, MD. The largest eye cancer center in America, the Oncology Service evaluates and treats approximately eight new cases of uveal melanoma and two new cases of retinoblastoma each week, and many of the most challenging cases from the U.S. and abroad are treated here. Dr. Firestone then served as a fellow in the Ocular Pathology Department at Wills Eye Hospital under the direction of Ralph C. Eagle, Jr., MD. The Pathology Department processes one of the largest volumes of ophthalmic specimens in the world.

Dr. Firestone has co-authored a book chapter on the topic of retinoblastoma and has published on the subject of combined hamartoma of the retina and retinal pigment epithelium. He is a diplomate of the American Board of Ophthalmology (ABO) and is a member of the American Academy of Ophthalmology (AAO) and the Oklahoma Academy of Ophthalmology (OAO). He sees adult and pediatric patients with suspected intraocular or periocular tumors at DMEI, and he sees cataract and other general ophthalmology patients both at the downtown and northwest Oklahoma City offices. He performs surgery at the McGee Eye Surgery Center, OU Medical Center, and the Children’s Hospital.

Dr. Firestone has been married to his lovely wife since 2005 and spends most of his time outside work with her and their four children.


  • American Association of Ophthalmic Oncologists and Pathologists (AAOOP)
  • International Society of Ocular Oncology (ISOO)
  • American Board of Ophthalmology (ABO)
  • American Academy of Ophthalmology (AAO)
  • Oklahoma Academy of Ophthalmology (OAO)
  • American Medical Society (AMA)

Honors and Awards

  • 1999 – Academic All-State Scholar | Oklahoma Foundation for Excellence
    Top 100 senior in an Oklahoma public high school
  • 2006 – Finalist, Vernino-Vannatta Award | OU College of Medicine
    Given to the sophomore medical student most able to demonstrate academic achievement, empathic understanding, and caring for others
  • 2012 – Chief Resident | Scott & White Eye Institute
  • 2012 – Finalist, Scott & White Hospital Outstanding Resident Award
    Given to the most outstanding resident physician in the entire Scott & White Memorial Hospital/Texas A&M University Health Sciences Center system
  • 2014 – William Neptune Distinguished Alumni Award | Oklahoma Baptist University
    Given to a single OBU alumnus for distinguished career achievement
  • 2017 – Edward & Thelma Gaylord Faculty Honor Award | Dean A. McGee Eye Institute
    Faculty award selected by resident physicians for most outstanding teacher
  • 2017 – Dewayne Andrews, MD Excellence in Teaching Award | U. of Oklahoma College of Medicine
    Outstanding resident teaching award from OU-COM Academy of Teaching Scholars
  • 2018 – Nominee, Aesculapian Award | OU College of Medicine, Class of 2019
    One of three nominees for outstanding medical student education in clinical sciences
  • 2018 – Member, Oklahoma Gazette “Forty Under 40”
    Program recognizing individuals in Central Oklahoma under 40 who have “achieved exceptional results and status in the business, creative, nonprofit, and governmental sectors of our community”


  • Schefler A, Skalet A, Oliver S, Mason J, Daniels A, Alsina KM, Plasseraud KM, Monzon FA, Firestone B. “Prospective evaluation of risk-appropriate management of uveal melanoma patients informed by gene expression profiling”. Melanoma Management. In press.
  • Muller L, Henson C, Firestone B, Ahmad S, Herman T, de la Fuente T. “Radiation Treatment to a Post-Resection Primary Mucoepidermoid Carcinoma (MEC) of the Conjunctiva with Positive Margins at the Tenon’s Fascia”. Medical Dosimetry. 2018;S0958-3947(18)30105-5. PMID 30366619.
  • Firestone BK, Arias JD, Shields CL, Shields JA. “Bilateral Combined Hamartomas of the Retina and Retinal Pigment Epithelium as the Presenting Feature of Neurofibromatosis Type 2 (Wishart type)”. Journal of Pediatric Ophthalmology & Strabismus. 2014;51. PMID 25922868.
  • Moreno Paramo D, Firestone B, Mahajan A, Gombos D. “Chapter 17: External Beam Radiation Therapy” Retinoblastoma. Editors: Ramasubramanian A., Shields C. Jaypee Brothers Medical Publishers, 2012.
  • Firestone BK, Mold JW, Scheid DC, Hamm RM. “Type 2 diabetes: Which interventions best reduce absolute risks of adverse events?” The Journal of Family Practice (Vol. 58, No. 6). Published online: June 2009.
  • Stray SJ, Johnson JM, Kopek BG, Zlotnick A. “An in vitro fluorescence screen to identify antivirals that disrupt hepatitis B virus capsid assembly.” Nature Biotechnology 24, 358-362. Published online: 12 February 2006.

Meet Dr. Firestone