- Undergraduate: University of Texas at Austin
- MD: University of Texas Medical Branch at Galveston
- Residency: Dean McGee Eye Institute
- Fellowship: Dean McGee Eye Institute
Dr. O’Brien is a native of Texas and earned his undergraduate degree from the University of Texas at Austin and his medical degree from the University of Texas Medical Branch at Galveston, where he was inducted into the Alpha Omega Alpha Honor Medical Society. He completed his internship at Houston Methodist Hospital, followed by a residency in ophthalmology at DMEI/OU. He served in outstanding fashion as Chief Resident during 2016-2017. He also completed a neuro-ophthalmology fellowship at DMEI/OU in 2017 - 2018.